Volgens Matsudo en kollega's
staat ME(CVS) geheel los van psychische aandoeningen (o.a. depressie).
Als een patiënt last heeft van psychische problemen (zoals depressie)
zouden beide zaken onafhankelijk van elkaar behandeld moeten worden, dus:
medische behandeling/supplelementen voor de ziekte !!
en een (niet-medikateuze) aanpak van de pyschische problemen.
Enkele citaten uit het studierapport
Russo et al., Skapinakis et al., and Wilson et al.
thought that
[the presence of comorbid psychiatric disorders]
predicted a poor prognosis for CFS...
No significant relationship was found
between the presence of comorbid psychiatric disorders and
the outcome of CFS.
The outcome of CFS
is independent from that of
comorbid psychiatric disorders, especially MDD,
which may be an important milestone
to clarify the pathophysiology of CFS and MDD.
In terms of
treatment programs for CFS patients in this study,
Hochuekki-to (TJ-41),
vitamin B12 and
C were prescribed,
however
antidepressants were not prescribed.
There is no report showing any effect of Hochu-ekki-to on MDD.
On the other hand,
antidepressants were not prescribed in our study,
because they are reported to produce a range of side-effects or
not to be effective for CFS when they are given to patients.
A two-year follow-up study of
chronic fatigue syndrome comorbid with psychiatric disorders
Psychiatry and Clinical Neurosciences. 2009. 63(3): 365-373.
Matsuda Y, Matsui T, Kataoka K, Fukada R, Fukuda S, Kuratsune H, Tajima S, Yamaguti K, Kato YH, Kiriike N.
Aims:
Chronic fatigue syndrome patients
often have comorbid psychiatric disorders
such as major depressive disorders and anxiety disorders.
However,
the outcomes of
chronic fatigue syndrome and
the comorbid psychiatric disorders
and the interactions between them
are unknown.
Therefore,
a two-year prospective follow-up study was carried out on
chronic fatigue syndrome patients
with comorbid psychiatric disorders.
Methods:
A total of 155 patients
who met the Japanese case definition of chronic fatigue syndrome
were enrolled in this study.
Comorbid psychiatric disorders
were diagnosed according to
the Diagnostic and Statistical Manual of Mental Disorders 4th edition criteria.
Patients with comorbid psychiatric disorders received psychiatric treatment
in addition to medical therapy for chronic fatigue syndrome.
Seventy patients participated in
a follow-up interview approximately 24 months later.
Results:
Of the 70 patients with chronic fatigue syndrome,
33 patients
were diagnosed as
having comorbid psychiatric disorders
including 18 major depressive disorders.
Sixteen patients with psychiatric disorders and
eight patients with major depressive disorders
did not fulfill the criteria of any psychiatric disorders
at the follow up.
As for chronic fatigue syndrome,
nine out of the 70 patients
had recovered at the follow up.
There is no significant influence
of comorbid psychiatric disorders
on the outcome of chronic fatigue syndrome.
Conclusions:
Chronic fatigue syndrome patients
have a relatively high prevalence of comorbid psychiatric disorders,
especially major depressive disorders.
The outcomes of
chronic fatigue syndrome and
psychiatric disorders
are independent.
Therefore
treatment of comorbid psychiatric disorders is necessary
in addition to the medical treatment
given for chronic fatigue syndrome.
KEYWORDS
chronic fatigue syndrome (CFS), comorbidity, major depressive disorder (MDD), outcome, psychiatric disorder
Published Online: 13 Apr 2009
DOI: 10.1111/j.1440-1819.2009.01954.x
Met dank aan Rob.
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